mercoledì 18 giugno 2008

Diabete e depressione


Questo interessante studio esamina il non ben chiarito rapporto bidirezionale tra diabete e depressione. Se infatti i sintomi di depressione sono associati con lo sviluppo di diabete di tipo 2 non è ancora chiaro quanto il diabete sia un fattore di rischio per lo sviluppo di depressione. L'analisi di circa 5000 pazienti diabetici sembrerebbe confermare questa associazione bidirezionale. Associazione che tuttavia sembrerebbe attenuarsi intervenendo sullo stile di vita.
Rimando alla lettura dell'articolo per i particolare.

iabetes and Depression -- A Two-Way Street

Depression may modestly increase the risk for incident type 2 diabetes -- and treated diabetes may increase the risk for depression -- reports JAMA.

Researchers examined associations between diabetes and depression among roughly 6800 adults aged 45 to 84 who were without cardiovascular disease at enrollment.

The first analysis, conducted among the 5200 subjects without baseline diabetes, found that those with baseline depression had significantly increased risk for developing diabetes during 3 years' follow-up. Adjustment for lifestyle factors, however, attenuated this association.

In the second analysis, comprising 4800 adults without depression at baseline, those with treated diabetes had significantly increased risk for depression during follow-up -- an association that persisted in fully adjusted analyses.

The authors call for studies to "determine whether interventions aimed at modifying behavioral factors associated with depression will complement current type 2 diabetes prevention strategies." They also suggest that providers consider routine depression screening among patients under treatment for type 2 diabetes.

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